As a domain administrator, you can set an auto-responder for any email account. Whenever an email is sent to that account, the sender receives an automated reply that you specify. In order to set an auto-responder for a particular email account -

1. Go to Mail >> Manage Users / Accounts in your control panel.
2. Click on the email account for which you wish to add the automated response.
3. On the account details page that follows, set the Auto-responder option to ON.
4. Specify the subject and content of the automated reply message. You can provide the content in either plaintext form, or in HTML.
5. Click on Save Changes.